The Endocannabinoid System and your Brain!

But how does it work?

And how does it have the ability to interact with ssynapseo many systems in the body? To understand this, a look at the endocannabinoid system will be helpful. The endocannabinoid system is a series of receptors throughout the body and is expressed everywhere from immune cells to cells in the brain. There are two currently known types of receptors in this system: CB1 and CB2. Generally speaking, CB1 cells are more highly expressed in the brain and central nervous system and CB2 receptors are found more in the periphery of the body and has a high expression in human immune cells, although there is some overlap.

The molecules that interact with these receptors are called Anandamide (AEA) and 2- Arachidonoylglycerol (2-AG). One of the many actions CBD and hemp extracts have on the endocannabinoid system is that they increase the levels of these signaling molecules in the body.

CBD has interesting actions in the human brain. It was originally studied for its ability to prevent seizures, but it is now being studied in relation to anxiety, depression, stress, and schizophrenia. It also could be able to prevent neurodegeneration, and can possibly prevent and dampen the stress response.

This is a really excellent research review of the neurological
benefits that CBD can have in the brain:

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5441138/

One of the most interesting studies I’ve found on CBD suggests that it can actually inhibit and turn off the stress response in the human body. One of the body’s main systems of stress is called the HPA-axis which stand for the Hypothalamic-Pituitary-Adrenal-Axis.

A researcher out of UW Milwaukee released a study suggesting that the endocannabinoid system signaling molecules could play an important role in this system. Her paper suggests that high levels of Anandamide may inhibit the fear response in the Amygdala and that high 2-AG levels may turn off the stress response.

Again, CBD has the ability to increase levels of both AEA and 2-AG in the body. CBD also seems to be able to increase neuroplasticity and growth of the hippocampus, which is involved in the stress response. 2 A growing number of studies in addition to lots of anecdotal stories from customers who have found CBD useful for stress and tension make us believe CBD is worth trying if you are struggling with mood or cognitive problems! (And let’s be honest, who couldn’t use some help there).

At Community Pharmacy, we carry multiple brands that we have researched for purity and potency and that we have found helpful. As far as dose, everyone is different. The best idea is to start with a low dose and slowly work up and notice how you feel. It seems like lower doses may actually work better for anxiety, whereas a dose that is too high may potentially exacerbate anxiety problems. Just another reason to start low and go slow!

If you’re taking psychiatric medications, talk to your practitioner and our pharmacists to make sure there won’t be any interactions between your medications and CBD.

Resources:

*1._ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6043845/
*2._  https://www.ncbi.nlm.nih.gov/pubmed/27889412

By: Brendan S.

Brendan works at Community Pharmacy and is passionate about giving people access to useful health related information. He is particularly interested in mental health and the interface between herbs, the microbiome and neurobiology. Find Brendan on the sales floor at the downtown pharmacy and on the internet.

Cooperator at Community Pharmacy

August Sales!

20% Off (Green Line Only)
Plus CBD………..Green Line Liquids, Capsules and Salve!
20%Off
Functional Remedies………Entire Line!
20% Off
Nordic Naturals……….All Gummies, Pet Products & more!
20% Off
Natural Factors…………Entire Line!
20% Off
Host Defense……….Lions Mane, Stamets 7, Mycoshield Sprays and, New Mushrooms Powders!
15% Off
Oregon’s Wild Harvest………(Select Herbs Only) Astragalus, Echinacea, Eleuthero, Maca, Milk Thistle and more!
15% Off
Puremedy………….All Salve!
20% Off
Pranarom………..All Hydrosols, Bug Bite Eraser, Bug Repellent Concentrate!
20% Off
Alaffia………..Hair Care and Kids Products!
 
20% Off
Acure…….. Hair Line!
…and many more great sales!
 
Bargain Basics……..Eclectic Institute………Select tinctures on sale!

You’ve Earned It!

EVERY Wednesday is Senior Discount Day at Community Pharmacy & Community Wellness Shop (Middleton).

10% off of your entire purchase (excluding prescriptions, sale and richarddiscontinued items) for those ages 60+.

Whether your goal is to participate in the National Senior Games or simply feel better doing everyday activities, we can help!

Visit Community Pharmacy & Community Wellness Shop to learn about supplements you can add to your routine to help you feel your best and stay active each and every day of your beautiful life.

WE ❤️ SENIORS !

Free CBD Lecture

cbd-class

What’s the deal with CBD?

Cannabidiol (CBD) is a hemp-derived nutrient that has been receiving a lot of attention for its benefits in health and well-being. It’s likely that you’ve heard from someone who is using it to control their stress or pain. Despite its popularity, there is a lot of confusion about this complex dietary ingredient. Let’s break the facts down together.

Join us in this informative lecture with our National Educator, Maggie Frank, as she discusses CBD’s interaction with the endocannabinoid system, how CBD was discovered, and much more!

Date: Wednesday July 24th

Time: 11am to 12:30pm

FREE EVENT

To register call Community Wellness at (608) 310-5390
Space is limited to 35 people.

Location: Community Wellness in Middleton, WI

 

 

 

 

July Sales!

4-of-july

15% Off………….Baxyl……… Hyaluronic Acid.baxyl

20% Off………. MegaFood………. All Products.

20% Off………Nutrigold………. All Herbs/Botanicals.

20% Off……….Nature’s Way……….Alive Multivitamins.

20% Off……….Nordic Naturals……….All Gummies, Pet Products & more!

gold20% Off……….Plus CBD………..Gold Drops & Raw Drops (Liquids Only).

20% Off……….Oregon’s Wild Harvest………(Select Herbs Only) Ashwagandha, Cranberry, Garlic, Ginger, Ginko, Milkthisle, Olive, St. Johns Wort, Valerian.

20% Off……….Natural Factors…………Omega3 Fish Oil, COQ10, Theracumin & more!

20% Off………..B&T………..Arnica Gel, Sssting Stop, and more B&T Gels and Creams!

20% Off………Host Defense……….Lions Mane, Stamets , Mycoshield Sprays, & Brain products.paleo-pro

20% Off………Paleo Pro………….Entire Line.

20% Off……..Barlean’s……….Omega Swirls.

20% Off………Ollois……….Homeopathic.

20% Off………Genexa Homeopathic……..

Including, allergy, kids, and Stress Relief.

20%Off………….American Health………Papaya Enzymes.

Bargain Basics……..Eclectic Institute………Select tinctures and Capsules.

20% Off………..Alaffia………..Face Care, Lip Balms, and Deodorants.

cana20% Off……….Desert Essence………..Toothpastes & mouthwash.

20% Off…………All Terrain……..Bug Products

20% Off…………..Pure Remedy…………All Salves.

20% Off…………..Andalou………Cannacell Line.

15% Off………..Four Elements………All Products.

15% Off…………Acure……….Select Face Care Items.

                                         ……………………………………….and many more great sales!

 

 

 

 

 

June Sales!

hemp
Hemp History Week June 3 to 9
CBD ……
20% Off…….. Plus CBD ………..(All Products).
20% Off……..Inesscents……..(Topical CBD Products).
Over All Health……
20% Off……..Nordic Naturals…….(Algae Omega, Complete Omega3 (60,120,180ct), Omega 3D (60,120CT), and more
20% Off……..Barlean’s……..(Omega Swirls).
20% Off……..Paleo Pro Proteins……..(All Products).
20% Off……..MegaFood……..(All Products).
20% Off…….Nutrigold…….(Vitamin C, Vitamin D3, Vitamin B, Vitamin E and Vitamin K).
20% Off……..Host Defense……..(Breathe, Cordyceps, Cordychi, Reishi, and Energy).
Body Care……
20% Off……..Alaffia……..(Liquid and Bar Soaps, Body Lotions, Body Washes, African Black Soap, Hand Soaps).
15% Off……..Puremedy…….(Topical Salves).
15% Off……..Four Elements……..(All Products).
Cackle Bee……..(New Low Prices).
……………………………………..and many more great sales!

We’re Hiring!

14976600_1506729219344024_9149682455640858911_oSALES TEAM MEMBER
Join our team at Community Pharmacy in Madison and Community Wellness Shop in Middleton and help us continue our 47 year tradition of quality service and wellness. We are an independent worker’s cooperative specializing in herbal and vitamin supplements, homeopathic remedies as well as a prescription pharmacy at our Madison location.

We are seeking a retail sales worker/buyer with excellent communication and customer service skills. Preferred candidates will possess nutritional/herbal knowledge, retail experience and a background in buying.

If working in a unique, cooperative business sounds desirable to you, stop by and pick up an application or download one from our HERE   or (under contact us).

This position averages 35 hours per week with a starting wage of $12.00 plus benefits. Spanish speakers are strongly encouraged to apply!

May Sales!

indexHere are just a few of the steals you won’t want to pass up

www-getmesomegreen-com-8-54521-00719-8-32CBD Oil

20% Off…….. Plus CBD ………..(All Raw RED Label Products & Gold Gummies).
Over All Health
20% Off……..Nordic Naturals…….(All Products).

20% Off……..Barlean’s……..(Omega Swirls).

ultimate-omega_soft-gel-liquid20% Off……..Eclectic……..(All Products).
20% Off……..Wish Gardens…….(All Products).
20% Off……..MegaFood……..(All Products).
20% Off……..Natural Vitality……..(All Products).
20% Off……..Enzymedica…….(All Products).
20% Off……..Oregon’s Wild Harvest……..(All Products).
20% Off……..American Health……..(Papaya Enzymes).
20% Off……..Nutrition Now……..(Gummy Vitamins & PB8 Probiotics).
20% Off……..Whole Earth and Sea……..(Multivitamins, Protein & Greens).
20% Off …….Natural Factors…….(Vitamin C, Vitamin D3, Vitamin B, & Stress-Relax Products).
20% Off……..Host Defense……..(Breathe, Cordyceps, Cordychi, Reishi, & Energy).
herbalarmor
Body Care
15% Off……..Four Elements…….(All Products)
15% Off……..Acure……..(Select Face Care Items).
20% Off……..All Terrain……..(Bug Repellents).
20% Off……..Alaffia……..(Babies and Kids Products).
20% Off……..Desert Essence……..(Toothpastes & Mouthwashes).
andalou
20% Off……..Andalou Face Care……..(Age Defying Line,Clarify Line, Quenching Line, Brightening Line, Sensitivity Line, Pod Masks, Sheet Mask).
Every Day Low Prices
20% Off……..Urbal Tea……..(All Products) New Low Prices!
20% Off……..Bloom Face Care……..(All Products).
New Products
15% Off……..Genexa Homeopathic……..(All Products).
…………………………………………………………………….and many more great sales!

footer_flowers-8712aa9cd808944b875ecdf544c143a95c1a52d9c4584942c2db0d158b46f9e3

April Sales

Here are just a few of the steals you won’t want to pass up:
CBD & Salves……
20% Off…….. Plus CBD ……(All Green Label Products)plus-cbd
20% Off………Charlotte’s Web………..(All Products).
20% Off………Functional Remedies………..(Hemp Oils Products). NEW!
Immune Health……
20% Off……..Host Defense……..(All products).
Over All Health……
20% Off……..Barlean’s……..(Omega Swirls).
20% Off…….. Nutrigold……..(Minerals and more).magnesium_calm
20% Off……..Natural Vitality……..(All Products).
20% Off……..Jarrow……..(All Products).
20% Off …….Natural Factors…….(All Products).
20% Off……..Nordic Naturals…….(Ultimate Omega Products)
Body Care……
20% Off……..Alaffia……..(Face and Lip Care).
20% Off……..Evan Healey……..(All Products).
15% Off……..Badger…….(Face Care Line).
Teas……
20% Off……..Pukka Teas……..(All Products). NEW!
20% Off……..Organic of India Teas ……..(All Products).
Goodies…..
20% Off……..Stasher……..(Silicone Pouches). NEW!pukka
……………………………………..and many more great sales!

Herbal Cold Prevention!

It’s that time of year again when cold viruses
frequently find their way to Community Pharmacy, accompanied by their sniffling, sneezing, and miserable human hosts. Colds are a huge moneymaker for the drug industry. An estimated 62 million colds per year leave millions of sick people roaming the aisles of pharmacies and grocery stores, desperate for relief. The cold virus, or Rhinovirus (RV), is transmitted via aerosol particles to hands, eyes and noses. Nasal epithelial cells are like a cozy little cottage for RV, providing the ideal pH and temperature for attachment and replication. A single sneeze may contain 20,000 viable droplets of RV that can be stable for 3-6 hours outside a host. That’s a lot of cold virus sitting on door knobs and checkout counters waiting for the next victim!
Cold symptoms start about 24-36 hours after infection. Affected cells trigger vasodilation, a natural part of the immune response, which leads to cough and runny nose. A healthy immune system will destroy most viruses within two days of infection. Within three to five days cold symptoms gradually diminish as cells start to heal from the inflammatory response. Collateral cell damage creates an opportunistic environment for secondary bacterial infection, which is why it’s crucial to rest, hydrate, and nourish the body during this critical period.
Obviously, cold prevention practices are easier said than done.
Here are a few simple tips that can help keep pesky RV (as well as other viral and bacterial pests) at bay.
 
1.- Stay well hydrated. Not only does dehydration weaken the immune response, it also impedes the function of mucus membranes in the nose and throat that protect us from invading viruses and bacteria.
2.- Eat high fiber and fermented foods such as yogurt, kefir, live sauerkraut, and kimchee every day. They support healthy gut microflora, which are an integral part of a strong immune system. Also consider taking a probiotic supplement. Research shows that regular probiotic use appears to lessen the chance of developing an upper respiratory tract infection (URTI).
3.- Have your vitamin D levels checked. Depending on the outcome, you might discuss the use of a vitamin D supplement with your health care provider. Vitamin D activates immune cells called T cells that kill foreign pathogens like RV. Low D levels keep the T cells from doing their job and are associated with a higher risk of URTI.
4.- Wash hands frequently and keep them away from your nose and eyes. This is one of the easiest and most effective ways to prevent the spread of RV.
Looking for some additional support during cold season? I’ve listed three of Community Pharmacy’s favorite herbal cold busters below.
Andrographis (Andrographis paniculata) has been used in its native Southeast Asia for centuries as an immune stimulant, anti-inflammatory, antipyretic and liver tonic herb. Current research shows andrographis to be very beneficial to the immune system, stimulating the immune response to infectious diseases of the respiratory tract. Its anti-inflammatory properties help calm the body’s natural inflammatory response to RV, lessening unnecessary cell damage and the subsequent discomfort of cold symptoms. When taken at the onset of symptoms, andographis has been shown to significantly shorten the course and duration of the common cold. For acute infections, a dosage of two grams daily has been shown to be most effective.
Energetically, andrographis is a cooling herb; herbalists and naturopaths feel it works best when combined with warming herbs like ginger, cinnamon, and astragalus. In Southeast Asia andrographis is a tenacious tenant of farms, fields, roadsides, and even seashores. This extreme ease of cultivation means it’s unlikely to be overharvested.
Echinacea (E. angustifolia, E. purpurea, E. pallida) is like a “designer herb” designated for the part of the immune system that targets RV. Commercial echinacea preparations made primarily from E. purperea and E. angustifolia are widely used for the treatment and prevention of URTIs. Some years ago echinacea received a bad rap based on negative outcome studies published in reputable medical journals. This confused practitioners and consumers who found echinacea beneficial to lessening symptoms and shortening the duration of colds. It turns out these studies overlooked critical aspects of proper echinacea use. Harvest conditions, processing, manufacturing, as well as the part of the plant used, will determine how it affects the immune system.
 
Echinacea Roots differ clinically from the aerial parts (flowers, seeds, leaves, and stems). Current consensus is that polysaccharides and/or lipoproteins in aerial parts of the plant have more immune-stimulating effects, while the roots block the inflammatory response and therefore lessen the cascade of symptoms it causes. Herbalists familiar with the most recent echinacea research recommend frequent dosing with echinacea root during the acute stages of a cold or flu. Lower doses of the aerial parts are generally reserved for stimulating and strengthening the immune system throughout cold season.
Black Elderberry (Sambucus nigra) berries are like tiny vehicles custom built to transport immune-boosting flavonoid compounds. These flavonoids help the body block RV and other respiratory viruses from attaching to the host cell wall, preventing it from entering and starting the viral replication process. Recent research has shown elderberry to be highly effective against various influenza viruses. An added benefit is that it boosts immune messenger cells called cytokines that trigger a healthy immune response to viral infections like RV and influenza. Perfectly safe for daily consumption, elderberry preparations are available as tinctures, capsules, lozenges, and syrups. I like to make cordials from fresh or dried berries.
Hopefully the cold prevention tips and herbal allies I’ve discussed will help keep you healthy this winter. Stop into Community Pharmacy to browse our expansive selection of immune support products and let us help choose the right one for you. As always, it’s a good idea to check with your practitioner before taking any supplement.
Carole Blemker is a Registered Nurse and Registered Dietitian with many years of experience. She is also a former librarian who loves researching all things concerning plants and people, and teaching from both holistic and clinical perspectives.